Yoga in regenerative medicine facilitates better recovery with ease by providing solutions for various diseases that plague mankind. The rebuilding of connective tissue via the technique of yoga and therapy is a highly reliable, natural, cost effective and a non surgical treatment option without any side effect and harm. Yoga is well known form of treatment from ancient days in rebuilding synaptic connection and the treatment of blood related disorder and respiration neuronal disorder in coordinating mind, body and spirit. Yoga and pranayama originated in India and is now being practiced all over the world to harvest its medicinal and therapeutics benefits in health care. Practicing yoga a non-invasive way to promotes trafficking of the stem cells from bone marrow tissue regeneration, repair and to take care of daily wear and tear and degenerating tissues.